In NetScaler Proxy mode, if a back-end server that supports an EDNS0 Client Subnet (ECS) sends a response containing the ECS option, the NetScaler appliance does the following:
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It forwards the response as-is to the client and
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Stores the response in the cache, along with the client subnet information.
DNS requests that are from the same subnet of the same domain, and for which the server would send the same response, are then served from the cache.
Note:
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ECS caching is disabled by default. Enable caching of EDNS0 client-subnet data in the associated DNS profile.
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The number of subnets that you can cache for a domain is limited to the available subnet IDs, that is, 1270 in the NetScaler appliance. Optionally, you can set the limit to a lower number (minimum value: 1 ipv4/ipv6).